Visian uses Collamer to provide the best optics and biocompatibility

 Alternative to LASIK surgery

Collamer: The Exclusive Material in the Visian ICLâ„¢

Collamer is a cutting edge lens material that is used exclusively in STAAR® Surgical Company corrective lenses, including several models of intraocular lenses (IOLs) and the myopic and toric implantable Collamer lens (ICL) models of the Visian ICL.

Collamer is a collagen containing lens material that provides extreme biocompatibility and excellent optical performance.   Collamer is derived from two words that describe the composition of the material which are called “Collagen” and “Co-polymer”.

Collamer is a 100 percent pure collagen copolymer material that is biologically and optically quiet in the eye. Collamer is easy to implant because it predictably unfolds gently in the eye.   Collamer transmits light in a way that is similar to the natural lens because the materials characteristics are nearly identical to the human crystalline lens.  The Collamer material is made by bonding collagen and UV absorbing chromophore into a poly-HEMA based copolymer.

The Collamer Advantage

Exclusive to STAAR Surgical Company, Collamer offers numerous advantages over other lens materials.

Quality of Vision

Built-in Anti-Reflective Interface of Collamer

Collamer has a built-in Anti-Reflective interface due to the surface having a higher water concentration than the bulk of the lens. 40 percent of the lens is comprised of water. The higher water concentration on the surface allows for a gradual change in refractive index from the aqueous (fluid inside the eye) to the lens. In fact, the light patterns associated with Collamer lenses are nearly identical to those of the human crystalline lens. As a result, less light is reflected, leading to a potential decrease in dysphotopsias 1.

Biocompatibility

Collamer-fibronectin bond halts foreign-body reaction

Collamer fosters compatibility of the lens in the eye by inhibiting the inflammatory response. Collagen in the Collamer material attracts fibronectin, a substance found naturally in the aqueous. A layer of fibronectin forms around the lens, inhibiting white cell adhesion to the lens. This coating prevents the lens from being identified as a foreign object, and the lens remains unnoticed and quiet in the eye indefinitely.

Charge repulsion with collagen significantly inhibits protein adhesion

Collagen in the Collamer lens carries a slight negative ionic charge. Likewise, proteins in the aqueous also possess a negative charge. As these two negative forces coincide along the lens/aqueous interface, charge repulsion repels the proteins, preventing their adhesion on the lens surface.

Collamer achieves it’s biocompatibility through two distinct mechanisms:

  • By preventing proteins and cells found naturally occurring in the aqueous from adhering to the lens surface.
  • By rendering the lens “invisible” to the body by promoting a monolayer of Fibronectin around the lens.

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